Histiocytic medullary reticulosis(HMR) is a rare, uniformly fatal, acute disease of the
reticuloendothelial system. Major clinical features are fever, malaise, weakness, weight
boss, lymphadenopathy, hepatosplenomegaly, jaundice and purfura. Common laboratory
findings are severe anemia, leukopenia, and thrombocytopenia. Cardinal pathologic
features are systematized proliferation of atypical, neoplastic, erythrophagocytic
histiocytes.
Recently we had opportunity to observe a patient with HMR at National Medical
Center.
The purpose of this report is to illustrate pertinent clinical and pathological featured of
this casts, and to review the cases reported in previous literatures.
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